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Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
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Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

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Percutaneous devices to support the left ventricle

David M Shavelle1, Leonardo Clavijo, Ray V Matthews

  • 1Division of Cardiovascular Medicine, University of Southern California, Los Angeles, CA, USA. shavelle@usc.edu

Expert Review of Medical Devices
|October 28, 2011
PubMed

Insights

This review covers percutaneous left ventricular assist devices (pLVADs) for high-risk procedures and cardiogenic shock. It details device function, implantation, hemodynamic effects, and clinical trial outcomes.

Area of Science:

  • Cardiology
  • Medical Devices
  • Interventional Cardiology

Background:

  • Percutaneous left ventricular assist devices (pLVADs) are emerging as crucial tools in managing complex cardiovascular conditions.
  • High-risk percutaneous coronary intervention (HR-PCI) and cardiogenic shock (CS) represent critical scenarios where mechanical circulatory support is often necessary.

Purpose of the Study:

  • To provide a comprehensive overview of the current landscape of three key percutaneous left ventricular assist devices.
  • To elucidate the technical aspects, including device composition and implantation procedures for pLVADs.
  • To analyze the hemodynamic alterations associated with pLVAD implantation and summarize clinical evidence.

Main Methods:

  • Literature review of published clinical trials and ongoing studies on selected pLVADs.
  • Analysis of technical specifications and device components.
  • Review of hemodynamic data from clinical studies and case reports.

Main Results:

  • Summary of the current status and technical features of three prominent pLVADs.
  • Discussion of expected and observed hemodynamic changes post-implantation.
  • Overview of clinical trial results for pLVADs in HR-PCI and CS populations.

Conclusions:

  • Percutaneous left ventricular assist devices offer a minimally invasive option for hemodynamic support in high-risk cardiac patients.
  • Further clinical trials are essential to define the optimal use and long-term outcomes of these devices.
  • pLVADs show promise in improving outcomes for patients undergoing HR-PCI and those in cardiogenic shock.

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