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Updated: May 28, 2026

Ratiometric Imaging of Extracellular pH in Dental Biofilms
Published on: March 9, 2016
Ratiometric sensing of fluoride anions based on a BODIPY-coumarin platform
Xiaowei Cao1, Weiying Lin, Quanxing Yu
1State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082, PR China.
Abstract:
Based on a new coumarin-BODIPY platform, compound 4 was rationally designed and synthesized as a novel ratiometric fluorescent sensor for fluoride anions. The sensor exhibited a large red shift (88 nm) in absorption and a drastic ratiometric fluorescent response (I(472)/I(606) = 17.4) to fluoride anions. Density function theory and time-dependent density function theory calculations were conducted to rationalize the optical response of the sensor.
