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Updated: May 28, 2026

A Mouse Model of Intestinal Partial Obstruction
Published on: March 5, 2018
Pseudodysplastic regenerative mucosa associated with congenital ileal atresia
Masakazu Fujimoto1, Hiromi Sakashita, Kengo Hattori
1Department of Pathology, Medical Research Institute, Kitano Hospital, Osaka, Japan. fujimasa@kuhp.kyoto-u.ac.jp
Abstract:
A male neonate was clinically diagnosed with congenital intestinal atresia. Surgical operation was performed and the ileum including the atretic portion was resected. Grossly, there was a plaque-like elevation of mucosa at the proximal side of the ileal atresia. Microscopic examination of this lesion revealed proliferation of severely atypical glands. Although dysplasia was a serious diagnostic concern, we concluded that ischemia due to the intestinal atresia induced this benign pseudodysplastic regenerative mucosa, judging from the pattern of coexisting inflammation and the literature review.
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