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Related Experiment Video

Updated: May 28, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
13:35

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

Published on: May 17, 2024

Reconstructive outcomes in patients undergoing contralateral prophylactic mastectomy.

Melissa A Crosby1, Patrick B Garvey, Jesse C Selber

  • 1Houston, Texas; and Baltimore, Md. From the Division of Surgery and the Departments of Plastic Surgery and Biostatistics, The University of Texas M. D. Anderson Cancer Center, and the Department of Plastic and Reconstructive Surgery, The Johns Hopkins Hospital.

Plastic and Reconstructive Surgery
|October 28, 2011
PubMed
Summary

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Immediate bilateral breast reconstruction after mastectomy shows similar complication rates between the index and prophylactic breasts. Surgeons should weigh the benefits of contralateral prophylactic mastectomy against potential surgical risks.

Area of Science:

  • Oncology
  • Plastic Surgery
  • Reconstructive Surgery

Background:

  • Increasing rates of contralateral prophylactic mastectomy (CPM) in breast cancer patients necessitate immediate bilateral breast reconstruction.
  • This study evaluates complication rates in both index and prophylactic breasts during simultaneous bilateral reconstruction.

Purpose of the Study:

  • To compare complication rates between immediate breast reconstructions for index cancer and prophylactic contralateral mastectomy.
  • To identify factors associated with postoperative complications in bilateral breast reconstruction.

Main Methods:

  • Retrospective review of 497 patients undergoing immediate bilateral breast reconstruction between 2005 and 2010.
  • Comparison of patient, tumor, reconstruction, and outcome characteristics between index and prophylactic breasts.

Related Experiment Videos

Last Updated: May 28, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
13:35

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

Published on: May 17, 2024

  • Classification by reconstruction method: implant, abdominal flap, or latissimus dorsi flap/implant.

    • Main Results:

    • Complication rates were similar for index (22.5%) and prophylactic (19.1%) reconstructions (p=0.090).
    • Overall, 20.3% of patients had complications in one breast, and 10.7% had complications in both.
    • Of patients with complications, 27.3% experienced them in the prophylactic breast.

    Conclusions:

    • Immediate bilateral breast reconstruction, including for prophylactic mastectomy, demonstrates comparable outcomes.
    • Careful consideration of oncologic benefits versus surgical morbidity is crucial for CPM decisions.