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Updated: May 28, 2026
Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
Published on: August 13, 2019
Molars extraction for bone graft study in rabbits
José Eduardo Ferreira Manso1, Carlos Fernando de Almeida Barros Mourão, Flávio Alexandre Lima Pinheiro
1Postgraduate Program in Surgical Sciences, UFRJ, Rio de Janeiro, Brazil.
Purpose:
The aim of this study was to describe an experimental surgical technique to be used in the evaluation of bone grafts in rabbits.
Methods:
The operative technique was performed in jaws, with external approach from the labial commissure to the last molar tooth. An incision about 1cm extended forward to the alveolar ridge, followed by a exposing the cervical region of the alveolar bone and dental elements was done. Thus, after extraction of first molar with forceps, the tooth socket left was filled with hydroxyapatite. The bone gain was analyzed by histopathological studies.
Results:
The histological analyses indicated formed bone surrounding the biomaterial.
Conclusion:
The experimental model using the tooth socket of the rabbit molar is a feasible procedure for studies of bone grafts.
