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Crohn's disease and hyperbaric oxygen therapy
Leonardo Estenio Iezzi1, Marley Ribeiro Feitosa, Bruno Amaral Medeiros
1Department of Surgery and Anatomy, FMRP, USP, Ribeirao Preto, SP, Brazil.
Acta Cirurgica Brasileira
|October 28, 2011
Summary
Hyperbaric Oxygen Therapy (HBO) shows promise for Crohn's disease (CD) patients unresponsive to medication. This treatment helped 11 out of 14 patients with abdominal, anorectal, or skin complications.
Area of Science:
- Gastroenterology
- Hyperbaric Medicine
Background:
- Crohn's disease (CD) is a chronic inflammatory bowel disease.
- Pharmacologic therapies are not always effective for CD management.
- Complications like abdominal, anorectal, and skin issues can arise in refractory CD.
Purpose of the Study:
- To assess the efficacy of Hyperbaric Oxygen Therapy (HBO) for Crohn's disease (CD) patients.
- To evaluate HBO's application in patients with CD refractory to standard pharmacologic treatments.
- To investigate HBO's impact on abdominal, anorectal, or skin complications associated with refractory CD.
Main Methods:
- A cohort of 14 patients with refractory Crohn's disease was selected.
- Patients received Hyperbaric Oxygen Therapy (HBO) at two medical centers.
- The study involved patients from the School of Medicine of Ribeirao Preto and the Center of Hyperbaric Medicine.
Main Results:
- Out of 14 evaluated patients, 11 demonstrated a satisfactory response to HBO.
- A significant positive outcome was observed in the majority of patients treated with HBO.
- HBO therapy was associated with successful management of complications in refractory CD.
Conclusions:
- Hyperbaric Oxygen Therapy (HBO) offers therapeutic benefits for Crohn's disease (CD) patients.
- HBO is a viable treatment option for refractory CD cases, particularly those with complications.
- The study suggests HBO can improve outcomes in patients with severe, treatment-resistant Crohn's disease.
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