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Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
Published on: September 18, 2013
Evaluation and management of lymphoma and leukemia in pregnancy
Jonathon B Cohen1, Kristie A Blum
1Department of Internal Medicine, Division of Hematology, The Arthur G. James Comprehensive Cancer Center and The Ohio State University, Columbus, Ohio, USA.
Abstract:
Cancer complicates roughly 1 in 1000 pregnancies with roughly 18% of these cases represented by the hematologic malignancies. These can range from an indolent lymphoma requiring only close monitoring to acute, life-threatening, processes requiring emergent therapy, and evaluation for potential termination of the pregnancy. Management of a pregnant woman with a hematologic malignancy requires a multidisciplinary approach combining the expertise of hematologists, obstetricians, and perinatologists to accomplish the best possible outcome. Many women are able to be treated successfully and deliver healthy babies.