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Updated: May 28, 2026

Z-Scores for Assessing Ovarian Reserve in Young Patients Undergoing Fertility Preservation
Published on: October 25, 2024
Diminished ovarian reserve and infertility
Shawn E Gurtcheff1, Nancy A Klein
1Seattle Reproductive Medicine, Seattle, Washington, USA.
Abstract:
Over the past several decades, social and demographic trends have led to an increased tendency for women to delay childbearing. Owing primarily to abnormalities in the oocyte and resulting embryonic aneuploidy, implantation, clinical pregnancy, and live birth rates decline sharply by the end of the fourth decade. As a result, the incidence of age-related infertility has increased. Improved awareness of the effects of aging on fertility combined with ovarian reserve assessment, patient education, and early infertility evaluation and intervention are important elements in appropriate family planning and prevention of age-related infertility.
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