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Related Concept Videos

Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Desmosomes01:05

Desmosomes

The term desmosome derives from the Greek words "desmo" and "soma" meaning "adhesion bodies." This structure was first observed during the late 1800s and described as small, dense nodules in the epidermis. Desmosomes are button-like structures that help form an interlinked network of intermediate filaments across the cells. These junctions are  essential to hold cells together under mechanical stress and to maintain tissue integrity. Desmosomes are multi-protein complexes comprising desmosomal...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Elastin is Responsible for Tissue Elasticity01:12

Elastin is Responsible for Tissue Elasticity

Elastic fiber contains the protein elastin along with lesser amounts of other proteins and glycoproteins. The main property of elastin is that it will return to its original shape after being stretched or compressed. Elastic fibers are prominent in elastic tissues found in skin and the elastic ligaments of the vertebral column.
Ligaments and tendons are made of dense regular connective tissue, but in ligaments not all fibers are parallel. Dense regular elastic tissue contains elastin fibers and...

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Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
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Papillary dermal elastosis.

Tracey Newlove1, Julia Tzu, Shane Meehan

  • 1Department of Dermatology, New York University, New York, New York, USA.

Dermatology Online Journal
|October 28, 2011
PubMed
Summary
This summary is machine-generated.

This study reports a rare case of papillary dermal elastosis, an acquired elastic tissue disorder, in a 36-year-old man. The findings highlight the importance of histopathology in diagnosing such unique skin conditions.

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Area of Science:

  • Dermatology
  • Histopathology
  • Medical Case Reports

Background:

  • Acquired disorders of elastic tissue present with diverse clinical and histopathologic features.
  • Accurate diagnosis relies on a combination of patient demographics, lesion characteristics, and microscopic examination.

Observation:

  • A 36-year-old male presented with multiple hypopigmented papules and plaques on the forearms, shoulders, chest, and back.
  • Lesions exhibited prominent follicular ostia and coalesced into larger patches.

Findings:

  • Histopathological examination revealed a selective loss of elastic fibers in the papillary dermis.
  • The observed clinical and histological features are consistent with papillary dermal elastosis.

Implications:

  • This case represents the second documented instance of papillary dermal elastosis.
  • Understanding rare elastic tissue disorders is crucial for accurate dermatological diagnosis and management.