Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Pharyngitis01:23

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Chronic Inflammation: Introduction01:12

Chronic Inflammation: Introduction

Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Partially Ablative Body Radiation Therapy Versus Standard Palliative Radiation Therapy for Locally Advanced Bulky Unresectable Sarcomas.

Advances in radiation oncology·2026
Same author

A Recombinant Antibody Against Human DRP1 Serine 616 Phosphorylation Enables Detection of BRAF<sup>V600E</sup>-Associated Mitochondrial Division in Cancer.

Antibodies (Basel, Switzerland)·2026
Same author

Localized granuloma annulare successfully treated with ruxolitinib.

JAAD case reports·2026
Same author

Leeches and hand surgery: history, physiology, and a scoping review.

Hand surgery & rehabilitation·2026
Same author

Relative survival analysis of dermatofibrosarcoma protuberans, Kaposi sarcoma, and pleomorphic sarcoma across intersectional demographics: A Surveillance, Epidemiology, and End Results (SEER) study.

Journal of the American Academy of Dermatology·2026
Same author

A Recombinant Antibody Against Human DRP1 Serine 616 Phosphorylation Enables Detection of BRAF <sup>V600E</sup> -Associated Mitochondrial Division in Cancer.

bioRxiv : the preprint server for biology·2026
Same journal

Pellagra associated with iron deficiency.

Dermatology online journal·2026
Same journal

Demodicosis: A frequently underrecognized cause of recalcitrant ear pruritus.

Dermatology online journal·2026
Same journal

Association of alopecia areata with COVID-19 vaccination: A vaccine adverse events reporting system analysis.

Dermatology online journal·2026
Same journal

Gender based price differences in 5% minoxidil foam: The impact of generic alternatives and bulk packaging.

Dermatology online journal·2026
Same journal

Retrospective analysis of filler complications reported in the manufacturer and user facility device experience database from 2015 to 2025.

Dermatology online journal·2026
Same journal

Characterizing barriers to care in patients with hidradenitis suppurativa.

Dermatology online journal·2026
See all related articles

Related Experiment Video

Updated: May 28, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
12:23

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

Cheilitis granulomatosa.

Amy E Rose1, Marie Leger, Julie Chu

  • 1Department of Dermatology, New York University, New York, New York, USA.

Dermatology Online Journal
|October 28, 2011
PubMed
Summary
This summary is machine-generated.

Melkersson-Rosenthal Syndrome (MRS) can present as incomplete cases, such as cheilitis granulomatosa (CG). This rare condition’s unknown cause makes treatment difficult, with recurrences common even with standard therapies.

Related Experiment Videos

Last Updated: May 28, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
12:23

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

Area of Science:

  • Neurology
  • Dermatology
  • Genetics

Background:

  • Melkersson-Rosenthal Syndrome (MRS) is a rare neurological disorder.
  • MRS is characterized by facial paralysis, persistent lip swelling (edema), and a fissured tongue.
  • Cheilitis granulomatosa (CG) is a rare condition that can be an isolated finding or part of MRS.

Observation:

  • This report details a case of cheilitis granulomatosa (CG) presenting as an incomplete form of Melkersson-Rosenthal Syndrome (MRS).
  • The patient's presentation highlights the variable clinical manifestations of MRS.
  • The etiology of CG and incomplete MRS remains largely unknown.

Findings:

  • Intralesional glucocorticoids are the primary treatment for CG but often result in symptom recurrence.
  • Alternative and combination therapies are being explored due to the limitations of current treatments.
  • Biologic agents, such as infliximab, show potential in managing refractory cases.

Implications:

  • Understanding incomplete MRS presentations like CG is crucial for timely diagnosis and management.
  • Exploring novel therapeutic strategies, including biologics, is essential for improving patient outcomes in rare conditions.
  • Further research into the pathogenesis of MRS and CG may lead to more targeted treatments.