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Related Concept Videos

Morphogenesis02:19

Morphogenesis

Plant morphogenesis—the development of a plant’s form and structure—involves several overlapping developmental processes, including growth and cell differentiation. Precursor cells differentiate into specific cell types, which are organized into the tissues and organ systems that make up the functional plant.
Forced Transdifferentiation01:28

Forced Transdifferentiation

Transdifferentiation, also known as lineage reprogramming, was first discovered by Selman and Kafatos in 1974 in silkmoths. They observed that the moths’ cuticle-producing cells transformed into salt-producing cells. Many such cases of natural transdifferentiation occur in organisms. In humans, pancreatic alpha cells can become beta cells. In newts, the loss of the eye’s lens causes the pigmented epithelial cells to transdifferentiate into the lens cells.
Artificial transdifferentiation occurs...
Gastrulation01:56

Gastrulation

Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata will form...
Cell Migration01:19

Cell Migration

Cell migration is a process by which the cells move from one location to another, playing an essential role in embryological development, repair and regeneration, immune response, and metastasis. Cells migrate in response to chemical or mechanical signals generated by specific organs or tissues. The overall mechanism includes three steps - polarization, protrusion, and release. Polarization involves the formation of a distinct cell front and rear, which determines the direction of movement.
Cell Migration01:09

Cell Migration

Cell migration, the process by which cells move from one location to another, is essential for the proper development and viability of organisms throughout their life. When cells are not able to migrate properly to their ordained locations, various disorders may occur. For example, disruption in cell migration causes chronic inflammatory diseases such as arthritis.
Zygotic Development And Stem Cell Formation01:10

Zygotic Development And Stem Cell Formation

The development of all multicellular organisms starts with the fusion of haploid cells called sperm and egg to form a diploid zygote. A zygote is a totipotent cell that can develop into a complete organism. The zygote undergoes cell division or cleavage to form an 8-cell mass. Until this stage, the cells are spherical, loosely attached, and remain totipotent. Totipotent cells are capable of developing both the embryonic and the extraembryonic tissues. However, as they continue to divide, they...

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Related Experiment Video

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Probing the Roles of Physical Forces in Early Chick Embryonic Morphogenesis
06:33

Probing the Roles of Physical Forces in Early Chick Embryonic Morphogenesis

Published on: June 5, 2018

Morphogenesis: forcing the tissue.

Andrew Fleming1

  • 1Department of Animal and Plant Sciences, University of Sheffield, Sheffield S10 2TN, UK. a.fleming@sheffield.ac.uk

Current Biology : CB
|October 29, 2011
PubMed
Summary
This summary is machine-generated.

Understanding how genetic instructions become physical form is crucial. Plant tissue analysis reveals that controlling the extracellular matrix is essential for organismal shape development.

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Tracking Morphogenetic Tissue Deformations in the Early Chick Embryo
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Last Updated: May 28, 2026

Probing the Roles of Physical Forces in Early Chick Embryonic Morphogenesis
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Probing the Roles of Physical Forces in Early Chick Embryonic Morphogenesis

Published on: June 5, 2018

Patterning the Geometry of Human Embryonic Stem Cell Colonies on Compliant Substrates to Control Tissue-Level Mechanics
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Tracking Morphogenetic Tissue Deformations in the Early Chick Embryo
08:19

Tracking Morphogenetic Tissue Deformations in the Early Chick Embryo

Published on: October 17, 2011

Area of Science:

  • Plant biology
  • Developmental biology
  • Biophysics

Background:

  • Organismal shape arises from complex developmental processes.
  • Transcriptional regulation plays a critical role in guiding development.
  • The physical mechanisms linking gene expression to form are not fully understood.

Purpose of the Study:

  • To investigate the link between transcriptional control and organismal morphology.
  • To identify the key physical factors mediating the transduction of genetic information into shape.
  • To explore the role of plant tissue mechanics in developmental processes.

Main Methods:

  • Analysis of plant tissue mechanical properties.
  • Investigating the extracellular matrix composition and dynamics.
  • Correlating gene expression patterns with physical characteristics.

Main Results:

  • Control over the extracellular matrix is a critical determinant of organismal shape.
  • Mechanical properties of plant tissues are directly influenced by extracellular matrix regulation.
  • Transcriptional events are effectively transduced into organismal form via modulation of tissue mechanics.

Conclusions:

  • The extracellular matrix is a key mediator in translating genetic blueprints into physical form.
  • Understanding plant tissue mechanics provides insights into fundamental developmental processes.
  • Targeting extracellular matrix components could offer novel strategies for controlling organismal development.