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Updated: May 28, 2026

Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Gold-catalyzed oxidative acyloxylation of arenes
Alexandre Pradal1, Patrick Y Toullec, Véronique Michelet
1Chimie ParisTech, Laboratoire Charles Friedel, UMR 7223 11 rue P. et M. Curie, 75231 Paris Cedex 05, France.
Abstract:
A variety of nonactivated hindered aromatic rings are acyloxylated (22 examples, up to 83% yield) in the presence of PPh(3)AuCl as the catalyst and di(acetoxy)iodobenzene as the oxidant. The reaction proceeds at 110 °C in an acid media and allows the formation of both hindered acetoxy and acyloxy derivatives. This methodology nicely complements the Pd-catalyzed arene acyloxylation reaction, which is not operating on hindered substrates and allows the Au-catalyzed unprecedented acyloxylation reaction of arenes, implying various carboxylic acids.
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