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Updated: May 28, 2026

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
Neurobrucellosis
1Department of Radiology, Cerrahpasa Medical Faculty, University of Istanbul, 34300 Kocamustafapasa, Istanbul. ebos90@hotmail.com
Abstract:
Brucellosis is a multisystem infection with a broad spectrum of clinical presentations. Its nervous system involvement is known as neurobrucellosis. Neurobrucellosis (NB) has neither a typical clinical picture nor specific cerebrospinal fluid (CSF) findings. Its diagnosis is based on the existence of a neurologic picture not explained by any other neurologic disease, evidenced by systemic brucellar infection and the presence of inflammatory alteration in CSF. Imaging findings of NB is divided into four categories: (1) normal, (2) inflammation (recognized by granulomas, abnormal enhancement of the meninges, perivascular space, or lumbar nerve roots), (3) white matter changes, and (4) vascular changes.
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