Cognitive functioning in older twins: the Older Australian Twins Study
Related Experiment Video
Updated: May 28, 2026

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
Published on: June 3, 2020
Perminder S Sachdev1, Teresa Lee, Andrea Lammel
1Brain and Ageing Research Program, School of Psychiatry, Faculty of Medicine, University of New South Wales, and Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, New South Wales, Australia. p.sachdev@unsw.edu.au
Aim:
To examine the concordance rates of common medical conditions and neurocognitive performance in monozygotic (MZ) and dizygotic (DZ) older twins.
Methods:
Twins aged ≥ 65 years and living in the three Eastern states of Australia were recruited through the Australian Twin Registry and underwent detailed neuropsychological and medical assessment.
Results:
Assessments were conducted on 113 MZ and 96 DZ twin pairs, with a mean age of 70.5 years. MZ twins were more concordant than DZ twins for hypertension and asthma. MZ twins had higher correlations than DZ twins on most neuropsychological tests, with the exception of some tests related to processing speed. The concordance rate for mild cognitive impairment or dementia was 76.2% in MZ twins and 42.9% in DZ twins, a non-significant difference.
Conclusions:
Except for some aspects of processing speed, most cognitive functions in older individuals show significant heritability. The heritability of neurocognitive disorders is, however, low.
More Related Videos
07:01Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment
Published on: September 20, 2020
10:13Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
Published on: February 14, 2014
Related Concept Videos
Cognitive Development During Adulthood
Case Studies
Cognitive Development During Adolescence
Biological Influences on Intelligence
Behavioral Genetics and Its Designs
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
Causes of Social Behavior II: Cognitive Processes