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Fragrance material review on 2-(4-methylphenoxy)ethanol
J Scognamiglio1, L Jones, C S Letizia
1Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ 07677, USA. jscognamiglio@rifm.org
Summary
This review examines the toxicology and dermatology of 2-(4-methylphenoxy)ethanol, a fragrance ingredient. Data on its physical properties, toxicity, and irritation potential were summarized for safety assessment.
Area of Science:
- Toxicology
- Dermatology
- Fragrance Ingredient Safety
Background:
- 2-(4-methylphenoxy)ethanol belongs to the Aryl Alkyl Alcohols (AAAs) structural group.
- AAAs are diverse fragrance ingredients characterized by an alcohol group bonded to an aryl group.
Purpose of the Study:
- To conduct a toxicologic and dermatologic review of 2-(4-methylphenoxy)ethanol.
- To summarize available data on the safety of this fragrance ingredient.
Main Methods:
- Comprehensive literature review of toxicology and dermatology studies.
- Evaluation and summarization of physical properties, acute toxicity, skin and eye irritation, and skin sensitization data.
Main Results:
- Summarized available data on 2-(4-methylphenoxy)ethanol.
- Data included physical properties, acute toxicity, skin irritation, eye irritation, and skin sensitization.
Conclusions:
- This review provides a detailed summary of data for 2-(4-methylphenoxy)ethanol.
- Findings contribute to the overall safety assessment of Aryl Alkyl Alcohols in fragrances (refer to Belsito et al., 2012).
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