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Updated: May 28, 2026

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
Published on: February 14, 2014
Gender differences in aging: cognition, emotions, and neuroimaging studies
1Neuropsychiatry Section, Department of Psychiatry, University of Pennsylvania Medical Center, Philadelphia, Pa, USA.
Gender and aging significantly impact brain functions. This study explores sex differences in cognitive and emotion processing, revealing distinct patterns in brain structure and activity between men and women.
Area of Science:
- Neuroscience
- Cognitive Science
- Gerontology
Background:
- Brain-behavior relationships are influenced by gender and aging.
- Neuroscience advances allow integrating neurobehavioral, neuroanatomic, and neurophysiology data.
Purpose of the Study:
- Examine cognitive and emotion processing in healthy men and women.
- Highlight sex differences and aging effects on brain-behavior relationships.
Main Methods:
- Neurobehavioral studies.
- Magnetic Resonance Imaging (MRI) for neuroanatomy.
- Functional imaging for brain activity.
Main Results:
- Progressive brain volume decrease affects frontotemporal regions more in men.
- Sex differences observed in blood flow, glucose metabolism, and receptor activity.
- Ovarian hormones play a role in observed gender-related brain-behavior patterns.
Conclusions:
- Integrating methodologies across the lifespan advances understanding of gender differences in healthy aging.
- Findings contribute to understanding brain disorders with a focus on gender.
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