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Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
Published on: January 20, 2023
Educational paper: Abusive Head Trauma part I. Clinical aspects
Tessa Sieswerda-Hoogendoorn1, Stephen Boos, Betty Spivack
1Section Forensic Paediatrics, Department of Forensic Medicine, Netherlands Forensic Institute, The Hague, The Netherlands. T.Sieswerda@amc.uva.nl
European Journal of Pediatrics
|October 29, 2011
Summary
Abusive Head Trauma (AHT), a common cause of childhood neurotrauma, often results from impact and shaking. Early diagnosis and a structured approach are crucial due to its high mortality and severe disability rates in affected children.
Area of Science:
- Pediatrics
- Neurology
- Child Abuse Research
Background:
- Abusive Head Trauma (AHT) is a leading cause of non-accidental childhood neurotrauma, previously known as shaken baby syndrome.
- AHT encompasses injuries from both shaking and impact, affecting approximately 14-40 infants per 100,000 annually.
- Mortality rates range from 15-23%, with survivors facing significant long-term neurological disabilities.
Purpose of the Study:
- To highlight the importance of recognizing AHT in pediatric neurotrauma cases.
- To emphasize the need for a structured diagnostic approach for clinicians.
- To underscore the challenges in diagnosis due to non-spontaneous reporting by caregivers.
Main Methods:
- Review of clinical findings associated with AHT.
- Analysis of incidence and outcomes in affected children.
- Identification of diagnostic indicators, including apnea as a distinguishing feature from accidental injury.
Main Results:
- AHT presents with diverse neurological signs, often with subdural hematomas as a common finding.
- Survivors experience significant disability, with up to half exhibiting IQs below the 10th percentile.
- Apnea is identified as a key differentiator between AHT and accidental trauma.
Conclusions:
- A high index of suspicion for AHT is warranted in children with neurological symptoms, especially when trauma history is minimal.
- Clinicians require comprehensive knowledge of AHT's signs, symptoms, risk factors, and diagnostic workup.
- A structured approach, akin to managing other lethal diseases, is essential for accurate AHT diagnosis and management.
