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Updated: May 28, 2026

5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat
Published on: July 3, 2013
[The follow-up of chronic renal failure]
1Clinique de Néphrologie-Dialyse, C.H.U. Brugmann, Bruxelles. frederic.collart@chu-brugmann.be
Insights
Managing chronic kidney failure requires establishing diagnosis and stage, then implementing strategies to slow disease progression. Key elements include renin angiotensin system blockade, cardiovascular risk control, and managing complications like anemia and phosphocalcic issues.
Area of Science:
- Nephrology
- Internal Medicine
Context:
- Chronic kidney failure (CKD) management is a prolonged and intricate clinical process.
- Accurate diagnosis of kidney disease and staging of renal failure are prerequisites for effective patient management.
- CKD necessitates a multifaceted approach addressing disease progression, cardiovascular risks, and complications.
Purpose:
- To outline a comprehensive strategy for the follow-up of patients with chronic kidney failure.
- To emphasize the importance of early diagnosis and staging in guiding CKD management.
- To detail the essential components of a CKD care strategy, including medical interventions and complication management.
Summary:
- Effective CKD follow-up involves establishing diagnosis and stage, followed by a strategy to slow disease progression.
- Key interventions include renin angiotensin system blockade and control of cardiovascular risk factors.
- Management also encompasses addressing complications such as anemia and phosphocalcic imbalances, alongside preparation for renal replacement therapy.
Impact:
- Optimized CKD management can slow disease progression and improve patient outcomes.
- Integrated care involving general practitioners and nephrologists is crucial for successful CKD follow-up.
- Proactive management of complications and preparation for dialysis or transplantation enhance quality of life for CKD patients.
Abstract:
The follow-up of chronic kidney failure is a long and complex process. The diagnosis of the kidney disease and the level of renal failure have first to be established. A strategy for slowing the evolution of chronic kidney disease has to be build. The blockade of the renin angiotensin system and the control of the cardiovascular risk factors are the main components of this strategy. The evaluation and the treatment of the classical complications of chronic kidney disease should also take place. Correction of anemia, and of phosphocalcic complications need specific therapies. Preparation for dialysis and transplantation have to be taken into account. Such a follow-up deserves a close collaboration between general practitioners and nephrologists.
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