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Updated: May 28, 2026

Retroductal Submandibular Gland Instillation and Localized Fractionated Irradiation in a Rat Model of Salivary Hypofunction
Published on: April 24, 2016
Salivary gland and associated complications in head and neck cancer therapy
Satish Kumar1, Saravanan Ram, Mahvash Navazesh
1University of Southern California, School of Dentistry, Division of Periodontology, Diagnostic Sciences and Dental Hygiene, Los Angeles 90089-0641, USA.
Abstract:
Xerostomia and salivary gland hypofunction are two of the most common and significant complications of head and neck cancer therapy in the head and neck region. This article will provide a brief overview of salivary gland hypofunction and associated complications in head and neck cancer therapy, mainly in radiation therapy. The discussion will include quality of life issues as well as current advances in cancer therapy to reduce xerostomia and salivary gland hypofunction.
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