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Updated: May 28, 2026

Retroductal Submandibular Gland Instillation and Localized Fractionated Irradiation in a Rat Model of Salivary Hypofunction
Published on: April 24, 2016
Management of xerostomia and salivary gland hypofunction
Saravanan Ram1, Satish Kumar, Mahvash Navazesh
1University of Southern California, School of Dentistry, Division of Periodontology, Diagnostic Sciences and Dental Hygiene, Los Angeles 90089-0641, USA.
Abstract:
Xerostomia and salivary gland hypofunction are conditions that have been associated with increased prevalence of caries, periodontitis, and candidiasis. Oral health care providers must be aware of the etiologies and clinical manifestations of salivary gland hypofunction in order to identify patients with this condition and to prevent its potential complications. The various modalities available to manage this condition range from frequent sips of water to the intake of systemic medications like pilocarpine or cevimeline.
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