Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Phase Contrast and Differential Interference Contrast Microscopy01:26

Phase Contrast and Differential Interference Contrast Microscopy

Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
Two-Dimensional Microscopy in Microbiology01:29

Two-Dimensional Microscopy in Microbiology

Two-dimensional (2D) microscopy encompasses a range of optical techniques that capture images within a single focal plane, offering detailed representations of microscopic structures. These techniques are essential in biological and medical research, enabling the visualization of cellular and subcellular structures with different levels of contrast and specificity.There are several major types of 2D microscopy, each with strengths and applications.Bright-Field MicroscopyBright-field microscopy...
Desmosomes01:05

Desmosomes

The term desmosome derives from the Greek words "desmo" and "soma" meaning "adhesion bodies." This structure was first observed during the late 1800s and described as small, dense nodules in the epidermis. Desmosomes are button-like structures that help form an interlinked network of intermediate filaments across the cells. These junctions are  essential to hold cells together under mechanical stress and to maintain tissue integrity. Desmosomes are multi-protein complexes comprising desmosomal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

3D Whole-body skin imaging for automated melanoma detection.

Journal of the European Academy of Dermatology and Venereology : JEADV·2023
Same author

The long-term evolution of melanocytic nevi among high-risk adults.

Journal of the European Academy of Dermatology and Venereology : JEADV·2022
Same author

Skin cancer risk among testicular germ-cell cancer survivors: a systematic review and meta-analysis.

Journal of the European Academy of Dermatology and Venereology : JEADV·2022
Same author

Sun Protection Behavior Following Skin Cancer Resection and Reconstruction.

Journal of cancer education : the official journal of the American Association for Cancer Education·2021
Same author

The differences in clinical and dermoscopic features between in situ and invasive nevus-associated melanomas and de novo melanomas.

Journal of the European Academy of Dermatology and Venereology : JEADV·2021
Same author

Development of a core outcome set for cutaneous squamous cell carcinoma trials: identification of core domains and outcomes.

The British journal of dermatology·2020

Related Experiment Video

Updated: May 28, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

White shiny structures: dermoscopic features revealed under polarized light.

T N Liebman1, H S Rabinovitz, S W Dusza

  • 1Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

Journal of the European Academy of Dermatology and Venereology : JEADV
|November 1, 2011
PubMed
Summary

White shiny structures in dermoscopy help differentiate skin cancers. Basal cell carcinoma often shows white shiny lines and areas, while melanoma may present short white lines orthogonally.

More Related Videos

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
09:37

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

Polarization-Sensitive Two-Photon Microscopy for a Label-Free Amyloid Structural Characterization
05:54

Polarization-Sensitive Two-Photon Microscopy for a Label-Free Amyloid Structural Characterization

Published on: September 8, 2023

Related Experiment Videos

Last Updated: May 28, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
09:37

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

Polarization-Sensitive Two-Photon Microscopy for a Label-Free Amyloid Structural Characterization
05:54

Polarization-Sensitive Two-Photon Microscopy for a Label-Free Amyloid Structural Characterization

Published on: September 8, 2023

Area of Science:

  • Dermatology
  • Dermoscopy
  • Oncology

Background:

  • White shiny structures (WSS) are unique polarized dermoscopy (PD) findings.
  • This study investigates WSS prevalence across melanoma, basal cell carcinoma (BCC), squamous cell carcinoma (SCC), actinic keratosis (AK), and lichen planus-like keratosis (LPLK).

Discussion:

  • BCC frequently exhibits combined white shiny areas and lines, often without organized patterns.
  • Melanoma WSS are characterized by short, orthogonally distributed white shiny lines, typically without white shiny areas.
  • Rosettes are more common in actinic tumors.

Key Insights:

  • The combination of white shiny lines and areas strongly suggests BCC.
  • Orthogonal, short white shiny lines without white shiny areas are indicative of melanoma.
  • Rosettes are a key feature of actinic tumors.

Outlook:

  • Differentiating skin neoplasms using WSS in PD can improve diagnostic accuracy.
  • Further research may refine WSS criteria for specific diagnoses.
  • Integration of WSS analysis into routine dermoscopic practice is recommended.