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Chicken Recombinant Limbs Assay to Understand Morphogenesis, Patterning, and Early Steps in Cell Differentiation
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1, 2, 3: counting the fingers on a chicken wing

Martin D Carkett1, Malcolm P O Logan

  • 1Division of Developmental Biology, MRC National Institute of Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.

Genome Biology
|November 1, 2011
PubMed
Summary

RNA sequencing of developing chick limbs resolved a long-standing debate on evolutionary homology between paleontologists and embryologists. This transcriptomic analysis provides key insights into limb development and evolutionary relationships.

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