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Updated: Jan 20, 2026

The Effect of Aspirin and Ibuprofen on the Phagocytic Ability of Macrophages
Published on: December 23, 2025
Aspirin-triggered metabolites of EFAs
Alexandros Makriyannis1, Spyros P Nikas
1Center for Drug Discovery, Northeastern University, Boston, MA 02115, USA. a.makriyannis@neu.edu
Abstract:
Aspirin triggers the biosynthesis of oxygenated metabolites from arachidonic, eicosapentaenoic, and docosahexaenoic (DHA) acids. In a preceding issue, Serhan et al. (2011) describe a novel aspirin-triggered DHA pathway for the biosynthesis of a potent anti-inflammatory and proresolving molecule.
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