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Updated: May 28, 2026

Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
Stigma: a core factor on predicting functionality in bipolar disorder.
Cem Cerit1, Arzu Filizer, Ümit Tural
1Department of Psychiatry, Haydarpaşa Numune Training and Research Hospital, Istanbul, Turkey. cemcerit@yahoo.com
Depression severity and perceived stigma significantly impact psychosocial functioning in bipolar disorder (BD) patients. Addressing these factors, alongside social support, is crucial for improving outcomes in remitted individuals.
Area of Science:
- Psychiatry
- Clinical Psychology
- Mental Health Research
Background:
- Bipolar disorder (BD) is linked to impaired psychosocial functioning.
- Predictors of functioning in remitted BD patients require further investigation.
Purpose of the Study:
- To identify demographic and clinical predictors of functioning in remitted BD patients.
- To examine the roles of social support, self-perceived stigma, and insight.
Main Methods:
- Eighty remitted BD patients were assessed using validated questionnaires.
- Data analyzed using t tests, Pearson correlations, and linear regression.
Main Results:
- Depression severity was the strongest predictor of functioning.
- Internalized stigma and perceived social support also significantly predicted functioning.
- Educational attainment and hospitalization history showed indirect effects.
Conclusions:
- Interventions targeting stigma reduction are vital for improving functioning in BD.
- Managing residual depressive symptoms is important for enhancing psychosocial outcomes.
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