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Related Concept Videos

Dosage Regimen: Fixed Dose01:01

Dosage Regimen: Fixed Dose

Fixed-dose regimens are a common approach to administer drugs to achieve and maintain desired levels of the drug in the body. In this dosing strategy, a specific amount of medication is given at regular intervals, often multiple times a day, to ensure a consistent drug concentration in the bloodstream.
Fixed-dose regimens can be used for various routes of administration, including intravenous (IV) injections and oral medications. For IV administration, a predetermined amount of the drug is...
Formulation and Manufacturing Process: Physical Attributes of Generic Tablets and Capsules01:18

Formulation and Manufacturing Process: Physical Attributes of Generic Tablets and Capsules

Bioequivalence in generic drugs, such as tablets and capsules, refers to their pharmaceutical equivalence to the brand-name counterparts. However, for therapeutic equivalence, manufacturers must also consider physical attributes like size, shape, and weight (FDA Guidance for Industry, December 2003). Discrepancies in these aspects could impact patient compliance and cause medication errors. For instance, swallowing difficulties, often experienced with larger tablets or capsules, can lead to...
Pharmaceutical Alternatives: Polymorphic Form-Related and Particle Size-Related Therapeutic Nonequivalence01:27

Pharmaceutical Alternatives: Polymorphic Form-Related and Particle Size-Related Therapeutic Nonequivalence

Changes in polymorphic forms can significantly influence the bioavailability of poorly soluble drugs. Although the FDA defines pharmaceutical equivalence based on having the same active ingredient, dosage form, and route of administration, it does not automatically disqualify products with different polymorphic forms. This means two products with different polymorphs can still be deemed pharmaceutically equivalent. However, polymorphic differences can affect properties like wettability,...
Pharmaceutical Equivalents01:26

Pharmaceutical Equivalents

As defined by regulatory standards, pharmaceutical equivalents require generic drug products to have identical dosage forms and chemically identical active pharmaceutical ingredients (APIs). They must adhere to compendial or applicable standards for potency, content uniformity, disintegration times, and dissolution rates. In the case of modified-release dosage forms, variations in drug content are permissible as long as the delivered amount remains consistent with the innovator drug product.
Dosage Regimens: Designs and Approaches01:28

Dosage Regimens: Designs and Approaches

Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
Dosage Regimen Designs: Nomograms and Tabulations01:23

Dosage Regimen Designs: Nomograms and Tabulations

Nomograms and tabulations are vital tools used by clinicians to design accurate and individualized dosage regimens. These instruments provide a straightforward method for adjusting dosages based on individual patient characteristics, including age, weight, and physiological condition. The foundation of a drug's nomogram is population pharmacokinetic data collected and analyzed using specific models. This data simplifies complex equations, presenting them diagrammatically or tabularly for easy...

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Quadruple-Checkerboard: A Modification of the Three-Dimensional Checkerboard for Studying Drug Combinations
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Pillbox: a solid dosage medication identification tool.

Emily Vardell1, David Goolabsingh, Vedana Vaidhyanathan

  • 1Calder Memorial Library , University of Miami Miller School of Medicine, Florida, USA. evardell@med.miami.edu

Medical Reference Services Quarterly
|November 2, 2011
PubMed
Summary
This summary is machine-generated.

Pillbox is a free online tool from the National Library of Medicine that helps identify medications. It enhances patient safety by quickly matching drug physical characteristics to database entries.

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Area of Science:

  • Pharmacology
  • Health Informatics
  • Drug Safety

Background:

  • Accurate medication identification is crucial for patient safety.
  • Healthcare professionals and patients need reliable tools for identifying solid dosage medications.
  • Existing identification methods may have limitations in speed or accessibility.

Purpose of the Study:

  • To introduce and describe the Pillbox tool for rapid identification of solid dosage medications.
  • To highlight the role of Pillbox in enhancing patient safety.
  • To compare Pillbox with similar resources and discuss future development.

Main Methods:

  • Users input physical characteristics (e.g., imprint, shape, color) of a medication.
  • The Pillbox database provides potential matches based on the input data.
  • Links to further drug information resources are offered.

Main Results:

  • Pillbox facilitates quick identification of solid dosage medications.
  • The tool provides users with potential matches and access to additional resources.
  • A comparative analysis with other identification tools was performed.

Conclusions:

  • Pillbox is a valuable tool for rapid medication identification, supporting patient safety.
  • The database, supported by the National Library of Medicine and FDA, offers a user-friendly interface.
  • Ongoing enhancements are planned to further improve the tool's utility.