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Updated: Aug 19, 2026

Ferric Chloride-induced Murine Thrombosis Models
Published on: September 5, 2016
Novel perspectives for structuring synthetic inhibitors of human blood platelet aggregation and potential
1Department of Medicinal Chemistry, College of Pharmacy, University of Tennessee, Memphis 38163.
Abstract:
An overview is presented on using molecular probes in tracing platelet function response patterns to specific structural features and physicochemical characteristics. Our carbamoylpiperidine nipecotoylpiperazine and related congeners are yielding new insights for as yet uncharted mechanisms of thrombocyte interaction dynamics, and the findings indicate promise for the development of novel potential antithrombotic agents.
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