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Related Experiment Video

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A Real-world What-Where-When Memory Test

A Real-world What-Where-When Memory Test

Published on: May 16, 2017

PARTNER B: where will it take us?

George R Reiss¹, Craig R Smith

¹Columbia University Medical Center-New York Presbyterian Hospital, New York, New York 10032, USA.

Seminars in Thoracic and Cardiovascular Surgery

|November 2, 2011

Summary

This summary is machine-generated.

Transcatheter aortic valve replacement (TAVR) significantly lowers mortality in symptomatic aortic stenosis (AS) patients ineligible for surgery. This minimally invasive procedure is now the standard of care, offering a life-saving alternative to medical management.

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Area of Science:

Cardiovascular Medicine
Interventional Cardiology
Medical Technology

Background:

Symptomatic aortic stenosis (AS) poses significant risks with standard medical therapy.
Surgical aortic valve replacement is not an option for all AS patients.
Transcatheter aortic valve replacement (TAVR) emerged as a less invasive alternative.

Purpose of the Study:

To evaluate the efficacy and safety of TAVR compared to standard medical therapy in patients with symptomatic AS who are not candidates for surgery.
To establish TAVR as a potential new standard of care for this patient population.

Main Methods:

The PARTNER trial, cohort B, compared TAVR to standard medical therapy.
Patient outcomes, including all-cause mortality, were assessed at one year.

Main Results:

TAVR demonstrated a 20% lower rate of death from any cause at one year compared to standard medical therapy.
Complication rates with first-generation TAVR devices were lower than anticipated.

Conclusions:

TAVR is a successful and effective treatment for symptomatic AS in patients unsuitable for surgery.
TAVR should be considered the new standard of care, despite unanswered questions regarding long-term durability and specific complications.