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[The DO2/VO2 relationship: and approach to cellular metabolism in "crisis" situations]
P Jolliet1, J F Pittet, J C Chevrolet
1Département d'anesthésiologie, Hôpital cantonal universitaire, Genève.
Schweizerische Medizinische Wochenschrift
|August 18, 1990
Abstract:
The relationship between the organism's oxygen consumption (VO2) and its transport to the cells (DO2), termed the DO2/VO2 relationship, has been the subject of many publications during the past decade. The pathological changes occurring in this relationship in intensive care patients has been much studied, and certain conclusions drawn with regard to monitoring and therapeutic goals. After a brief review of the pathophysiological mechanisms involved we examine the practical implications of the DO2/VO2 concept, focusing on the many methodological and interpretation problems raised.