[The clinical outcomes of patients undergoing revascularization for acute coronary syndrome]
Jun-ping Kang1, Chang-sheng Ma, Qiang Lü
1Department of Cardiology, Beijing Anzhen Hospital of Capital Medical University, Beijing 100029, China. kangjunping@126.com
Insights
Revascularization offers similar survival rates for ST-segment elevation myocardial infarction (STEMI), non ST-segment elevation myocardial infarction (NSTEMI), and unstable angina (UA) patients. Unstable angina patients experienced fewer major adverse cardiovascular and cerebrovascular events (MACCE).
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Clinical Prognosis
Context:
- Acute coronary syndrome (ACS) encompasses STEMI, NSTEMI, and unstable angina (UA).
- Coronary revascularization is a key intervention for ACS.
- Prognostic outcomes following revascularization vary among ACS subtypes.
Purpose:
- To evaluate the short-term and long-term prognosis of coronary revascularization in ACS patients.
- To compare mortality and major adverse cardiovascular and cerebrovascular events (MACCE) rates across STEMI, NSTEMI, and UA cohorts.
- To analyze the impact of ACS type on post-revascularization outcomes.
Summary:
- A study of 6005 patients undergoing revascularization for ACS (STEMI, NSTEMI, UA) between 2003-2005, with follow-up through 2006.
- No significant differences in in-hospital or late mortality (18-month survival: 96-98%) were observed among STEMI, NSTEMI, and UA groups.
- Patients with unstable angina demonstrated a lower MACCE rate (89% survival) compared to STEMI and NSTEMI (86% survival).
Impact:
- Revascularization provides comparable long-term survival for STEMI, NSTEMI, and UA patients.
- Unstable angina patients may benefit from a reduced risk of MACCE post-revascularization.
- Findings inform clinical decision-making and risk stratification for ACS management.
Objective:
To evaluate short-term and long-term prognosis of revascularization in patients with acute coronary syndrome.
Methods:
A total of 6005 patients who received coronary revascularization in our institution between July 2003 and September 2005 were enrolled. The patients were followed up in clinic or by telephone after discharge between September 2006 and November 2006. The clinical and prognosis data of all-cause mortality, neo-myocardial infarction, nonfatal stroke, and re-revascularization of ST-segment elevation myocardial infarction (STEMI), non ST-segment elevation myocardial infarction (NSTEMI) and major adverse cardiovascular and cerebrovascular events (MACCE) were analyzed.
Results:
Among 4865 acute coronary syndrome patients, 955 cases were STEMI; 263 cases were NSTEMI; and 3647 cases were unstable angina (UA) pectoris. There were no significant difference for in-hospital mortality and late mortality (18 month survival 96%, 98% and 98%) between patients with STEMI, NSTEMI and UA. Patients with UA had lower MACCE rate (18 month non-MACCE survival of STEMI, NSTEMI and UA group were 86%, 86%, and 89% respectively).
Conclusions:
Despite different clinical characteristics, patients with STEMI, NSTEMI and UA undergoing revascularization had similar short-term and long-term mortality. Patients with UA had lower MACCE rate.
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