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[Comparison and analysis of different diagnostic criteria for peripartum cardiomyopathy]
Yan Wang1, Zhan Gao, Guo-li Liu
1Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing 100044, China.
Insights
Chinese peripartum cardiomyopathy (PPCM) diagnostic criteria, particularly obstetric guidelines, show significant differences from international standards. Internal medicine criteria align better with the Hibbard criteria for diagnosing PPCM.
Area of Science:
- Cardiology
- Obstetrics & Gynecology
- Internal Medicine
Background:
- Peripartum cardiomyopathy (PPCM) is a rare form of heart failure.
- Accurate diagnosis is crucial for timely management and improved outcomes.
- International diagnostic criteria, such as the Hibbard criteria, exist alongside national guidelines.
Purpose of the Study:
- To compare the diagnostic criteria for peripartum cardiomyopathy (PPCM) used in Chinese obstetrics and internal medicine with the established Hibbard criteria.
- To identify discrepancies and similarities between Chinese and international diagnostic standards for PPCM.
- To analyze reasons for non-compliance between Chinese and international PPCM diagnostic criteria.
Main Methods:
- A retrospective analysis of 49 patients diagnosed with PPCM between March 1995 and September 2009.
- Comparison of patient diagnoses against Chinese obstetric criteria, Chinese internal medicine criteria, and Hibbard criteria.
- Analysis of compliance rates and reasons for non-compliance, including timing, presence of other causes, and echocardiographic findings.
Main Results:
- Chinese obstetric criteria showed a low compliance rate (25%) with Hibbard criteria for PPCM diagnosis.
- Chinese internal medicine criteria demonstrated a significantly higher compliance rate (83%) with Hibbard criteria.
- Common reasons for non-compliance included unmet timing criteria, presence of other determinable causes (like preeclampsia), and echocardiographic findings not meeting diagnostic standards.
Conclusions:
- Significant differences exist between Chinese and Hibbard diagnostic criteria for PPCM.
- Chinese internal medicine criteria for PPCM diagnosis are more consistent with international standards than Chinese obstetric criteria.
- Further refinement of PPCM diagnostic criteria in China may be warranted to improve diagnostic accuracy and patient care.
Objective:
To compare the differences and similarities between the diagnostic criteria of obstetrics and internal medicine in China with that of Hibbard for peripartum cardiomyopathy (PPCM).
Methods:
From March 1995 to September 2009, a total of 49 patients were diagnosed as PPCM at the Peking University People's Hospital and the Fu Wai Hospital in Beijing, China. Obstetric diagnostic criteria was: PPCM was one of dilated cardiomyopathy, occurred during the third trimester of pregnancy through the 6th month postpartum, and without cardiovascular diseases before. Internal medicine diagnostic criteria was: PPCM was unexplained cardiomegaly and heart failure, occurred during the last month of pregnancy through the 5th month postpartum, and meet the echocardiographic criteria of dialated cardiomyopathy as follows:left ventricular end-diastolic dimension (LVEDd) greater than 5.0 cm; left ventricular ejection fraction (LVEF) less than 45%, and(or) left ventricular fractional shortening (LVFS) less than 30%; or LVEDd greater than 2.7 cm/body surface area (m2); or LVEDd>117% of age and body surface area predictive value. Hibbard diagnostic criteria was: All four of the following: (1) heart failure within last month of pregnancy and 5 months postpartum; (2) absence of prior heart disease; (3) no determinable cause; (4) strict echocardiographic indication of left ventricular dysfunction: LVEF less than 45%, and/or LVFS less than 30%, and LVEDd greater than 2.7 cm/m2. The compliance between obstetric and internal criteria with Hibbard criteria, and the reasons of incompliance between Chinese and international criteria were analyzed.
Results:
Eight patients were diagnosed of PPCM by obstetricians according to Chinese obstetric criteria. Among them, 6 patients (6/8) did not meet Hibbard criteria.2 of the six did not reach the time regulated in the criteria. All of the six had other determinable causes for heart failure, and their echocardiographic results did not meet the diagnostic standard either. The other 41 patients were diagnosed of PPCM by physicians according to Chinese internal medicine criteria. Among them, 7 patients (17%) did not meet Hibbard criteria, 3 of the seven did not reach the time regulated in the criteria, and had other determinable causes for heart failure either.4 of the seven did not meet the echocardiographic standard part in the criteria. The Chinese internal medicine diagnostic criteria has a significant higher coincidence rate with Hibbard criteria, compared to Chinese obstetric criteria (83% vs. 25%; P<0.01). Among all 13 patients whose PPCM diagnosis did not meet Hibbard criteria, 5 cases did not reach the time regulated in the criteria, 9 cases had other determinable causes for heart failure, and 10 cases did not meet the echocardiographic standard part in the criteria. Preeclampsia was the most common determinable causes for heart failure, accounted for 7 cases.
Conclusion:
There is obvious difference between Chinese and Hibbard diagnostic criteria for PPCM, especially Chinese obstetric criteria.
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