Related Experiment Video
Updated: May 28, 2026

Cancer-Associated Fibroblasts from Mouse Mammary Tumors as Tools for Molecular and Computational Studies
Published on: July 3, 2025
kConFab: a familial breast cancer consortium facilitating research and translational oncology
Heather Thorne1, Gillian Mitchell, Stephen Fox
1Research Department, PeterMacCallum Cancer Centre, St Andrew's Place, East Melbourne, Victoria 3002, Australia. heather.thorne@petermac.org
Abstract:
In 2005, 100,514 Australians were diagnosed with cancer, and over 10,000 of these cancers will be due to heritable causes. The impact of familial cancer by definition extends beyond the individual, affecting tens of thousands of parents, siblings, and children. The study of familial cancer causes has arguably made the greatest single contribution to our understanding of cancer biology. This knowledge is used clinically to guide investment in screening and prevention, as well as being translated into new treatments.
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