Intermittent peritoneal dialysis in acute kidney injury

The mortality rate of acute kidney injury (AKI) patients is high despite of new advanced continuous renal replacement therapy (CRRT), which has widely become the treatment of choice in patients who are hemodynamically unstable. Nevertheless, the effectiveness of CRRT in improving the survival outcome is still unclear. Therefore, many centers still use intermittent peritoneal dialysis (IPD) or intermittent hemodialysis (IHD) in hospital where CRRT is unavailable. The present study was carried out to evaluate outcome of AKI patients who were treated with IHD and IPD in Saraburi Hospital.

A retrospective study of AKI patients requiring dialysis during 2004 to 2009 was conducted. Patients who were under 15 years old or underwent more than one modality of dialysis were excluded. Demographic data and mode of RRT were analyzed for survival.

Of all 145 patients, 101 were admitted into ICU. Mean age of patients was 61.6 +/- 17.8 years and 60.7% of all patients were male. Acute tubular necrosis was the most common cause of AKI, whereas volume overload was the leading indication for RRT. Overall mortality was 68.3%. There was no statistically significant difference in mortality rate between the two modes of dialysis.

The mortality rate of AKI patients is high despite having dialysis support. There is no statistically significant difference in mortality rate between IHD and IPD among these patients.