Related Experiment Video
Updated: May 28, 2026

Embryo Microinjection Techniques for Efficient Site-Specific Mutagenesis in Culex quinquefasciatus
Published on: May 24, 2020
1-Phenylisoquinoline larvicidal activity against Culex quinquefasciatus
Rodolfo Quevedo1, Edwin Baquero, Martha L Quiñones
1Departamento de Química, Facultad de Ciencias , Universidad Nacional de Colombia, Bogotá, Colombia. arquevedop@unal.edu.co
Abstract:
The larvicidal potential of several dopamine 1-phenylisoquinoline derivatives against Culex quinquefasciatus third instar larvae was investigated in a rational search for insecticides. The results showed that these isoquinolines presented moderate larvicidal activity, that the presence of a substituent is needed on carbon 1 for such activity to be presented and that it may be possible to develop novel insecticidal compounds having potential use in controlling insects by appropriate structural modification of 1-phenylisoquinolines. This article presents a possible structure-larvicidal activity relationship for isoquinolinic compounds.
Related Concept Videos
Anthelminthic Agents
Oxidation of Phenols to Quinones
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox property is crucial in...

