Related Experiment Video
Updated: Aug 19, 2026

Photodynamic Therapy with Blended Conducting Polymer/Fullerene Nanoparticle Photosensitizers
Published on: October 28, 2015
Photosensitization by selected anticancer agents
K Reszka1, J A Hartley, J W Lown
1Department of Chemistry, University of Alberta, Edmonton, Canada.
Abstract:
Novel anticancer anthrapyrazoles and anthracenediones are available as alternatives to the cardiotoxic clinical agents, doxorubicin and daunorubicin. Certain representatives of these new classes of compounds possess photosensitizing properties. The structural features influencing the photophysical parameters of these agents are discussed. Photosensitizing reactions involving singlet oxygen production, free radical formation, decomposition of hydrogen peroxide and organic hydroperoxides, oxidation of certain biochemical electron donors, DNA damage and killing of human leukemic cells in vitro in the presence of photoactive anthrapyrazoles, anthracenediones and anthracyclines are described.
More Related Videos
Related Concept Videos
Targeted Cancer Therapies
There are several types of targeted therapies against specific...
Treatment Resistant Cancers
Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Mutations
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
Targeted Cancer Therapies
There are several types of targeted therapies against specific...
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

