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Fully automatic synthesis of [¹⁸F]FES for reporter gene hERL expression imaging

Sheng Liang1, Xiaoli Lan, Yongxue Zhang

  • 1Department of Nuclear Medicine, Ruijin Hospital, School of Medicine, Institute of Med-X, Shanghai Jiaotong University, Shanghai, China.

Nuclear Medicine Communications
|November 3, 2011
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Reporter Genes02:11

Reporter Genes

Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
Commonly used reporter...