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Updated: May 28, 2026

A Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology
Published on: February 7, 2015
Relation between carotid intima-media thickness and aortic knob width in patients with essential hypertension
Hakan Erkan1, Levent Korkmaz, Mustafa Tark Ağaç
1Department of Cardiology, Ahi Evren Heart and Vascular Surgery Training and Research Hospital, Turkey.
Insights
Aortic knob width on chest X-rays can help predict subclinical atherosclerosis in hypertensive patients. This simple measurement correlates with carotid intima media thickness, offering valuable cardiovascular risk information.
Area of Science:
- Cardiovascular Imaging
- Radiology
- Hypertension Research
Background:
- Subclinical atherosclerosis assessment is crucial for hypertensive patients.
- It aids in evaluating hypertension severity and cardiovascular risk.
Purpose of the Study:
- To evaluate the utility of aortic knob width on chest radiography.
- To assess subclinical atherosclerosis in hypertensive individuals.
Main Methods:
- 126 hypertensive patients were analyzed.
- Carotid intima media thickness (CIMT) was measured.
- Aortic knob width was measured on chest radiographs.
Main Results:
- Aortic knob width strongly correlated with CIMT (r=0.62, P<0.001).
- CIMT also correlated with age, systolic, diastolic, and pulse pressures.
- Aortic knob width, age, and systolic pressure were independent predictors of CIMT.
Conclusions:
- Aortic knob measurement on chest X-rays is a useful tool.
- It provides predictive information for subclinical atherosclerosis in hypertension.
Objective:
The assessment of subclinical atherosclerosis is important in the evaluation of a hypertensive patient, as it provides information on the severity of the hypertension and the cardiovascular risk. The aim of this study was to determine the usefulness of the aortic knob width measured on chest radiography in the assessment of subclinical atherosclerosis in hypertensive patients.
Method And Results:
A total of 126 consecutive hypertensive patients were enrolled. In univariate analysis, there was a strong correlation between carotid intima media thickness (CIMT) and aortic knob width (r=0.62, P<0.001). In addition, there were statistically significant correlations between CIMT and age (r=0.42, P<0.001), systolic pressure (r=0.27, P=0.02), diastolic pressure (r=0.28, P<0.03), and pulse pressure (r=0.31, P<0.001). In linear regression analysis, the aortic knob width (β=0.5, P<0.001), age (β=0.02, P=0.03), and systolic pressure (β=0.03, P=0.005) were the only independent predictors of CIMT.
Conclusion:
Observation of aortic knob on chest radiograph in hypertensive patients may provide important predictive information of subclinical atherosclerosis.
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Special considerations while measuring blood pressure
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
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