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Updated: May 28, 2026

Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation
Published on: January 17, 2019
A neurological complication of a uterine fibroid
Jonathan Graff-Radford1, David T Jones, Rajiv K Pruthi
1Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
Background:
Uterine leiomyoma (or fibroid) can be associated with secondary polycythemia and venous thrombosis, but there has been no report of intracranial venous thrombosis associated with leiomyoma.
Methods:
We describe a case report of a cerebral venous thrombosis associated with erythrocytosis and a uterine fibroid in a non-smoking female with no history of malignancy or hormone use. The hemoglobin and erythropoietin normalized after removal of her uterine fibroid.
Results:
MRI/MRV of this 60-year-old cephalalgic female revealed extensive thrombus throughout the sagittal sinus and right transverse sinus. CT of the abdomen revealed a 16 × 13 × 12 cm solid mass arising for the uterus consistent with a uterine fibroid. PET scan was negative for malignancy. Hemoglobin on admission was 18.4 g/dl. Erythropoietin was 16.6 mIU/ml. One month after hysterectomy, her hemoglobin was 12.6 g/dl and her erythropoietin was 4.7 mIU/ml.
Conclusions:
Cerebral vein thrombosis is a potential complication of uterine fibroids with erythrocytosis.
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