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Spontaneous liver tumors in aged germfree Wistar rats
Laboratory Animal Science
|February 1, 1979
Abstract:
Liver tumors, ranging from benign nodules to carcinomas, developed spontaneously in 115 (87%) of 132 germfree Wistar rats beyond the age of 30 months. In addition, the rats developed a high incidence of benign adenomas of endocrine glands and of the breasts.
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