Related Experiment Video
Updated: May 28, 2026

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
Published on: January 7, 2019
[Contribution of mathematical modeling to vaccination decision making. Examples from varicella, rotavirus and
1Institut de Veille Sanitaire--94415 Saint-Maurice cedex. d.levybruhl@invs.sante.fr
Abstract:
The decision to add a new vaccine to the immunization schedule is a complex and multidisciplinary process based on the risk-benefit balance and, increasingly, on the cost- effectiveness ratio. Such decisions now use mathematical models that can predict the indirect, and potentially detrimental, effects of mass vaccination on the epidemiology of the target disease. The adjunction of an economic component to the modeling process ensures that vaccination represents an efficient allocation of available financial resources in an increasingly constrained environment.
Related Concept Videos
Vaccinations
Mathematical Modeling: Problem Solving
Impact of Pharmacokinetic–Pharmacodynamic Models: Regulatory Decisions
Fundamental Mathematical Principles in Pharmacokinetics: Calculus and Graphs
On the other hand, integral calculus focuses on...
Vaccines
Smallpox

