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Published on: November 7, 2017
[Cardiorenal syndrome]
Viviana Aursulesei1, A Cozma, M D Datcu
1Universitatea de Medicină şi Farmacie "Gr. T. Popa" Iaşi, Facultatea de Medicină, Clinica I Medicală Cardiologică.
Insights
Cardiac and renal disease frequently coexist, leading to cardiorenal syndrome. This review clarifies the complex pathophysiology, diagnosis, and treatment of this deadly association.
Area of Science:
- Cardiology
- Nephrology
- Internal Medicine
Context:
- Cardiac and renal diseases often coexist, increasing mortality and healthcare costs.
- The cardiorenal syndrome describes the heart-kidney interaction, lacking a consensus definition.
- Limited data exist on incidence, pathophysiology, and diagnostic criteria for cardiorenal syndrome.
Purpose:
- To provide a comprehensive overview of the cardiorenal relationship.
- To elucidate the complex pathophysiology, epidemiology, diagnosis, and treatment of cardiorenal syndrome.
- To offer clearer perspectives on future therapeutic strategies for this condition.
Summary:
- This paper reviews the multifaceted aspects of cardiorenal syndrome.
- It addresses the intricate interactions between cardiac and renal systems.
- The review covers pathophysiology, epidemiology, diagnostics, and treatment challenges.
Impact:
- Aims to improve understanding and management of cardiorenal syndrome.
- Highlights the need for standardized definitions and diagnostic criteria.
- Informs future therapeutic approaches for this deadly cardiorenal association.
Abstract:
Cardiac and renal disease are common and frequently coexist, resulting in increased risk of mortality, morbidity and cost of care. The interaction between heart and kidney is refered to as cardiorenal syndrome, but a consensus definition has not been established. Also, there are limited data about the true incidence, the pathophisiology is poorly understood and standardized diagnostic criteria are lacking. Because the process is complex, treatment can be a challenge despite the novel therapies. This paper addresses all the complex interactive aspects of the cardiorenal relationship, from pathophysiology to epidemiology, diagnosis and treatment, to have more clear perspectives on the future therapeutic approaches to this deadly association.
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