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Antibiotic prophylaxis considering patient outcome from percutaneous endoscopic gastrostomy

Mădălina-Paula Cosmulescu1, J N Russell

  • 1"Gr.T.Popa" University of Medicine and Pharmacy, Iasi.

Revista Medico-Chirurgicala a Societatii De Medici Si Naturalisti Din Iasi
|November 4, 2011
PubMed

Insights

Antibiotic use, particularly prophylaxis, can significantly reduce the risk of infection after Percutaneous Endoscopic Gastrostomy (PEG) tube placement. Early placement also aids patient recovery and transfer to less acute care settings.

Area of Science:

  • Gastroenterology
  • Surgical Procedures
  • Infectious Disease

Background:

  • Percutaneous Endoscopic Gastrostomy (PEG) is a common procedure for patients with neurological conditions or stroke.
  • Peristomal wound infection is a known complication following PEG insertion.
  • Adherence to established guidelines is crucial for optimizing patient outcomes.

Purpose of the Study:

  • To evaluate the effectiveness of antibiotic prophylaxis in reducing peristomal wound infections after PEG placement.
  • To analyze the incidence of complications and mortality associated with PEG insertion.
  • To assess the impact of early PEG placement on patient care pathways.

Main Methods:

  • Retrospective analysis of 75 patients undergoing PEG insertion at West Cumberland Hospital (September 1999 - October 2007).
  • Evaluation of antibiotic prophylaxis protocols, procedural outcomes, and postoperative complications.
  • Comparison of outcomes with guidelines from the British Association of Gastroenterologists.

Main Results:

  • Infection was the most frequent postoperative complication.
  • Antibiotic prophylaxis demonstrated a reduction in peristomal wound infection rates.
  • No immediate procedural complications were reported in the analyzed cohort.

Conclusions:

  • Antibiotic use, including prophylaxis or concurrent administration, is effective in minimizing peristomal wound infections post-PEG.
  • Early PEG placement can facilitate patient transition to non-acute care environments.
  • The study findings support the implementation of evidence-based practices for PEG insertion.
Abstract

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