Related Experiment Video
Updated: May 28, 2026
11:49
Single-port Non-liposuction Endoscopic Axillary Lymph Node Dissection in Breast Cancer Surgery
Published on: April 3, 2026
[The lymph nodes status--prognostic factor in breast cancer]
V G Rugină1, D Mihalcea, Florentina Pricop
1Universitatea de Medicină şi Farmacie "Gr. T. Popa" Iaşi, Facultatea de Medicină, Spitalul Obstetrică Ginecologie "Cuza Vodă" Iaşi.
Summary
Assessing axillary lymph node status in breast cancer patients is crucial for survival prediction. Dissecting 10 or more lymph nodes and using adjuvant therapy significantly improves patient outcomes.
Area of Science:
- Oncology
- Surgical Pathology
Context:
- Breast cancer prognosis is significantly influenced by axillary lymph node status.
- Accurate staging requires detailed pathological examination of lymph nodes.
Purpose:
- To evaluate the survival rates based on axillary lymph node status in breast cancer patients.
- To determine the prognostic value of lymph node involvement and adjuvant therapy.
Summary:
- A study of 206 women with breast cancer analyzed 5-year survival rates in relation to lymph node status.
- Survival was significantly impacted by lymph node positivity, number of involved nodes, and adjuvant systemic therapy.
- Pathological examination of axillary nodes provides valuable survival information.
Impact:
- The findings highlight the importance of axillary lymph node assessment for predicting breast cancer patient survival.
- Identifying lymph node metastasis and utilizing adjuvant therapies are key to improving survival rates.
Related Concept Videos
01:23Detailed Structure and Function of Lymph Nodes
Lymph nodes are bean-shaped structures that cluster along the lymphatic vessels in the inguinal, axillary, and cervical regions. Each node is divided into compartments by a capsule that extends trabeculae inward.
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...
02:07Tumor Progression
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...