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[Incidence of congenital malformations in the Iaşi "Cuza Vodă" Maternity Hospital]
Monica Titianu1, Carmina Schaas, Maria Stamatin
1Universitatea de Medicină şi Farmacie "Gr. T. Popa" Iaşi, Facultatea de Medicină.
Insights
Congenital malformations are a significant concern, affecting 3.52% of newborns. Early prenatal diagnosis is crucial to identify fetal abnormalities and reduce neonatal mortality.
Area of Science:
- Perinatology
- Medical Genetics
- Public Health
Context:
- Congenital malformations represent a major cause of neonatal mortality.
- This study analyzes a decade of data on congenital malformations in a specific region.
- The research highlights regional disparities in accessing advanced prenatal diagnostic techniques.
Purpose:
- To provide updated data on the incidence of congenital malformations.
- To underscore the critical role of prenatal diagnosis in managing fetal abnormalities.
- To assess the impact of congenital malformations on neonatal mortality rates.
Summary:
- A ten-year study encompassing 2211 cases of congenital malformations revealed a prevalence of 3.52%.
- Over 11% of affected pregnancies resulted in miscarriage or termination due to fetal abnormalities.
- Neonatal mortality remains high, with many infants succumbing shortly after birth.
Impact:
- Emphasizes the need for widespread access to advanced prenatal diagnostic tools.
- Highlights the importance of accurate fetal assessment to prevent unexpected diagnoses at birth.
- Informs public health strategies aimed at reducing the burden of congenital malformations.
Aim:
To update the data on the incidence of congenital malformations in our area and emphasize the importance of prenatal diagnosis.
Material And Methods:
The study was conducted over a period of ten years and included 2211 cases with congenital malformations. Such parameters as the incidence of malformations over these years, gestational age at the moment of diagnosis, and mortality from congenital malformations were followed. Statistical and graphical data were processed with the help of SPSS 16.0 and MS Excel software.
Results:
The total prevalence of malformations was 3.52%, comparable with the data in the literature. Over this period a number of 262 cases (11.8%) ended in spontaneous miscarriage or termination of pregnancy for fetal abnormalities. A significant percentage of these pregnant women gave birth to their child, many of them dying shortafter.
Conclusions:
Congenital malformations remain the leading cause of mortality in neonates. In Romania, the advanced techniques of prenatal diagnosis being used only in specialized centers, and a large number of cases may escape early diagnosis. This study underlines the importance of a correct assessment of fetuses so that the discovery of fetal abnormalities at birth not to be a surprise.
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