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Updated: May 28, 2026

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis
Published on: June 3, 2018
[Morphopathological changes in glaucoma-induced trabecular meshwork]
D Petraru1, Anca Indrei, D Costin
1Universităţii de Medicină şi Farmacie "Gr.T. Popa" Iaşi.
Unlabelled:
Glaucoma causes trabecular meshwork and Schlemm canal changes, resulting in the obstruction of the aqueous flow at this level.
Aim:
To show the histological changes in the surgically removed trabecular meshwork tissues.
Material And Method:
Trabecular meshwork fragments were histologically processed for histological diagnosis.
Results:
29.87% of all patients had ordered structure with high eosinophilia, 20.12% a rare structure with high eosinophilia, 21.34% a voluminous trabecular meshwork with fusiform cells, 21.03% tissue fibrosis and 7.62% had tissue necrosis.
Conclusions:
Aqueous flow obstruction in trabecular meshwork is produced by the histological changes at this level, found in all tissue specimens removed during surgery.
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