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Updated: May 28, 2026

Measuring Volatile and Non-volatile Antifungal Activity of Biocontrol Products
Published on: December 5, 2020
[Antimicrobial activity of some cinnamic acid derivatives]
Alexandra Jităreanu1, Gabriela Tătărîngă, Ana-Maria Zbancioc
1Universitatea de Medicină şi Farmacie "Gr. T. Popa" Iaşi, Facultatea de Farmacie, Disciplina de Chimie Organică.
Abstract:
Due to drug-resistance phenomenon, there is a constant need for discovering new antiinfectious agents. A series of cinnamic acid derivatives was synthesized and then brominated with bromine in the presence of chloroform or acetic acid. The structure of the new compounds was confirmed by elemental and spectral data. Their antimicrobial activity was tested by disc-diffusion method. The tested compounds had mainly antifungal activity and were moderately active against Gram-positive bacteria. Bromination of the double bond determined the enhancement of the antimicrobial activity for all the tested compounds.
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