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Association between the results of the childhood asthma control test and objective parameters in asthmatic children

Yasunori Ito1, Yuichi Adachi, Toshiko Itazawa

  • 1Department of Pediatrics, Faculty of Medicine, University of Toyama, Toyama, Japan.

The Journal of Asthma : Official Journal of the Association for the Care of Asthma
|November 4, 2011
PubMed

Insights

The Childhood Asthma Control Test (C-ACT) correlates with lung function in children with asthma. A C-ACT score of 23 may identify children with normal lung function, but it does not reflect airway inflammation.

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Medicine
  • Clinical Assessment Tools

Background:

  • The Childhood Asthma Control Test (C-ACT) is a questionnaire used to assess asthma control in children.
  • Its ability to reflect objective measures of asthma severity, such as airflow limitation and airway inflammation, requires further investigation.

Purpose of the Study:

  • To evaluate the correlation between the Childhood Asthma Control Test (C-ACT) scores and objective measures of asthma control, specifically airflow limitation (%FEV1) and airway inflammation (FeNO).
  • To determine the utility of the C-ACT in identifying children with normal lung function.

Main Methods:

  • A cohort of 258 asthmatic children (aged 5-11 years) completed the Japanese version of the C-ACT.
  • Lung function tests (measuring %FEV1) and fractional exhaled nitric oxide (FeNO) measurements were performed.
  • Statistical analyses, including correlation and receiver operating characteristic (ROC) curve analysis, were used.

Main Results:

  • A significant positive correlation was found between C-ACT scores and %FEV1 (r = 0.317, p < .001).
  • The C-ACT demonstrated 71.5% accuracy in identifying subjects with normal lung function (%FEV1 >80%), with an optimal cutoff score of 23.
  • No significant relationship was observed between C-ACT scores and FeNO levels, indicating it does not reflect airway inflammation.

Conclusions:

  • A C-ACT cutoff score of 23 may aid in identifying children with well-controlled asthma and normal lung function.
  • The C-ACT does not appear to reflect airway inflammation, suggesting a need for improved tools to assess this aspect of asthma control in pediatric populations.
Abstract

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