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Updated: May 28, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
Ruptured thoracoabdominal aneurysm in a 27-year-old with hyper IgE syndrome
Orwa Falah1, Stephen E Thwaites, R T A Chalmers
1Department of Vascular Surgery, Royal Infirmary of Edinburgh University Hospital, Edinburgh, United Kingdom. orwafalah@hotmail.com
Abstract:
Hyperimmunoglobulin E syndrome is a rare primary immunodeficiency disorder defined by high serum immunoglobulin E titers and associated with characteristic infectious, dermatologic, skeletal, and dental abnormalities. We present the case of a 27-year-old man presenting acutely with a ruptured type IV thoracoabdominal aortic aneurysm. He was successfully treated by open operative repair and discharged with long-term prophylactic antibiotics. To our knowledge, this is the first such case reported in the English literature.
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