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Related Experiment Video

Updated: May 27, 2026

Collection of Post-mating Semen from the Female Reproductive Tract and Measurement of Semen Liquefaction in Mice

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Published on: November 18, 2017

[A combined method for weighing human semen volume].

Xin-zong Zhang¹, Kang-shou Yao, Cheng-liang Xiong

¹Research Institute of Family Planning, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China. zxz20090722@sohu.com

Zhonghua Nan Ke Xue = National Journal of Andrology

|November 5, 2011

Summary

Accurate human semen volume measurement is crucial for clinical analysis. A combined method of electronic balance weighing and volumetric cylinder measuring provides precise results, surpassing individual techniques.

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Last Updated: May 27, 2026

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Area of Science:

Reproductive Medicine
Andrology
Biometry

Context:

Precise human semen volume measurement is essential for reliable clinical semen analysis.
Existing methods like electronic balance weighing and volumetric cylinder measuring have limitations in accuracy.
The Zhejiang Human Sperm Bank collected data from 137 donors, analyzing 492 semen samples.

Purpose:

To identify a precise method for measuring human semen volume.
To provide reliable evidence for clinical semen analysis and research applications.

Summary:

A combined method, integrating electronic balance weighing and volumetric cylinder measurement with a derived formula, was evaluated against individual methods.
The combined method yielded a mean semen volume of (3.46 +/- 1.17) ml.
Paired sample t-tests revealed the combined method's superiority over electronic balance weighing (3.75 +/- 1.21 ml) and volumetric cylinder measuring (3.22 +/- 1.16 ml).

Impact:

The combined method offers accurate semen volume determination, addressing the overestimation by electronic balance weighing and underestimation by volumetric cylinder measuring.
This validated technique is recommended for widespread clinical and research use in andrology.
Improved accuracy in semen volume measurement can enhance the reliability of fertility assessments and related research.