Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Inflammation: Introduction01:12

Chronic Inflammation: Introduction

Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Inflammatory Bowel Disease II: Ulcerative Colitis01:20

Inflammatory Bowel Disease II: Ulcerative Colitis

Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal BarrierA...
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Pancreatitis II: Pathophysiology01:21

Chronic Pancreatitis II: Pathophysiology

Chronic pancreatitis is a progressive and irreversible inflammation of the pancreas, most often caused by long-term alcohol abuse, but it can also be related to ductal obstruction, smoking, or genetic factors.Chronic pancreatitis occurs when the pancreas is repeatedly exposed to harmful agents like alcohol, smoking, ductal obstruction, or genetic predisposition. These factors lead to the release of toxic metabolites and inflammatory cytokines, sustaining chronic inflammation in the pancreatic...
Acute Inflammation III: Local and Systemic Effects01:25

Acute Inflammation III: Local and Systemic Effects

Acute inflammation produces a coordinated set of local and systemic changes that limit injury, eliminate pathogens, and initiate repair. These responses arise within minutes of infection, trauma, or chemical insult and are driven by vascular alterations and leukocyte-derived mediators. When the stimulus resolves, the reaction typically abates within days.Local EffectsAt the site of injury, arteriolar vasodilation increases blood flow, resulting in redness and warmth. Simultaneously, increased...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Advances in the studies of concealed penis].

Zhonghua nan ke xue = National journal of andrology·2015
Same author

[Application of tunica dartos flap coverage to tubularized incised plate urethroplasty].

Zhonghua nan ke xue = National journal of andrology·2013
Same author

[Diagnosis and treatment of epididymal obstructive azoospermia by microsurgery].

Zhonghua nan ke xue = National journal of andrology·2012
Same author

[Distribution and composition of organochlorine pesticides in farmland top soils of Anhui Province].

Ying yong sheng tai xue bao = The journal of applied ecology·2012
Same author

[Tea polyphenols protects the testis following testicular torsion/detorsion in rats].

Zhonghua nan ke xue = National journal of andrology·2010
Same author

[Indwelling the anterior urethral stent: a good treatment option for anterior urethral stricture].

Zhonghua nan ke xue = National journal of andrology·2010
Same journal

[Research progress on multimodal precision nursing interventions in urinary incontinence rehabilitation management after radical prostatectomy].

Zhonghua nan ke xue = National journal of andrology·2025
Same journal

[Dietary intervention to improve erectile dysfunction: Progress in research].

Zhonghua nan ke xue = National journal of andrology·2025
Same journal

[Tonifying kidney and activating blood therapy for the treatment of diabetic erectile dysfunction: A systematic review and meta-analysis].

Zhonghua nan ke xue = National journal of andrology·2025
Same journal

[Clinical effect of Huotujiji prescription on patients with asthenospermia of spleen-kidney yang-deficiency type].

Zhonghua nan ke xue = National journal of andrology·2025
Same journal

[Application of predictive nursing to the rehabilitation of patients after endoscopic surgery for prostate under the concept of enhanced recovery after surgery].

Zhonghua nan ke xue = National journal of andrology·2025
Same journal

[Influencing factors of lower urinary tract symptoms in patients after radical prostatectomy and nursing strategy].

Zhonghua nan ke xue = National journal of andrology·2025
See all related articles

Related Experiment Video

Updated: May 27, 2026

Measurement of Tactile Allodynia in a Murine Model of Bacterial Prostatitis
06:46

Measurement of Tactile Allodynia in a Murine Model of Bacterial Prostatitis

Published on: January 16, 2013

[Chronic prostatitis and cytokines].

Qing-xin He1, Xue-de Li

  • 1No. 181 Hospital of the Chinese People's Liberation Army, Guilin, Guangxi 541002, China.

Zhonghua Nan Ke Xue = National Journal of Andrology
|November 5, 2011
PubMed
Summary
This summary is machine-generated.

Cytokines play a crucial role in chronic prostatitis (CP) and chronic pelvic pain syndrome (CPPS). Understanding these inflammatory mediators is key for classifying and treating these common male conditions.

More Related Videos

Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation
09:49

Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation

Published on: August 13, 2015

Transurethral Instillation Procedure in Adult Male Mouse
04:01

Transurethral Instillation Procedure in Adult Male Mouse

Published on: November 2, 2017

Related Experiment Videos

Last Updated: May 27, 2026

Measurement of Tactile Allodynia in a Murine Model of Bacterial Prostatitis
06:46

Measurement of Tactile Allodynia in a Murine Model of Bacterial Prostatitis

Published on: January 16, 2013

Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation
09:49

Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation

Published on: August 13, 2015

Transurethral Instillation Procedure in Adult Male Mouse
04:01

Transurethral Instillation Procedure in Adult Male Mouse

Published on: November 2, 2017

Area of Science:

  • Immunology
  • Urology
  • Molecular Biology

Context:

  • Chronic prostatitis (CP) is a prevalent condition in men with unclear pathogenesis.
  • Inflammation, inflammatory cells, and cytokines are integral to CP development and progression.

Purpose:

  • To review the role of cytokines in the pathogenesis of CP and CPPS.
  • To explore the significance of cytokines in CP/CPPS classification and diagnosis.

Summary:

  • Cytokine dysregulation is implicated in all forms and stages of chronic prostatitis.
  • Cytokines are vital for understanding the immunological and molecular mechanisms underlying CP and CPPS.
  • Applying cytokine knowledge aids in the classification and treatment strategies for CP/CPPS.

Impact:

  • Highlights the importance of cytokines in diagnosing and managing chronic prostatitis.
  • Provides insights into novel therapeutic targets for CP and CPPS based on cytokine profiles.
  • Enhances understanding of the inflammatory pathways involved in chronic pelvic pain conditions.