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Published on: March 3, 2023
Exercise-induced respiratory symptoms not due to asthma
Chetan A Pandit1, Eugenie Batterby, Peter Van Asperen
1Department Respiratory Medicine, The Children's Hospital at Westmead, Westmead Discipline of Paediatrics & Child Health, Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.
Exercise can reveal hidden diagnoses like stridor from double aortic arch or vocal cord dysfunction, even when initially mistaken for asthma. A detailed history and lack of response to asthma treatment are key to identifying these conditions.
Area of Science:
- Pediatrics
- Respiratory Medicine
- Diagnostic Challenges
Background:
- Exercise-induced symptoms are often initially attributed to asthma.
- Misdiagnosis can lead to prolonged, ineffective treatment and persistent exercise limitation.
- Conditions like stridor and vocal cord dysfunction can mimic exercise-induced asthma.
Purpose of the Study:
- To highlight the importance of considering alternative diagnoses in patients with exercise-induced respiratory symptoms.
- To emphasize the diagnostic value of detailed patient history, including during exercise.
- To underscore the significance of treatment response in differentiating conditions.
Main Methods:
- Case report analysis of two pediatric patients with exercise-induced symptoms.
- Detailed clinical history taking, focusing on symptom characteristics during physical exertion.
- Evaluation of response to standard asthma treatments, specifically bronchodilators.
Main Results:
- An 8-year-old boy with presumed asthma was diagnosed with exercise-induced stridor due to a double aortic arch compressing the trachea.
- A 13-year-old boy presented with exercise-induced stridor, diagnosed as vocal cord dysfunction, initially treated as exercise-induced wheeze.
- Neither patient responded to bronchodilator therapy, prompting further investigation.
Conclusions:
- Thorough patient history, including symptom specifics during exercise, is crucial for accurate diagnosis.
- Lack of response to bronchodilators in the absence of typical asthma signs warrants consideration of alternative diagnoses.
- Conditions like double aortic arch and vocal cord dysfunction should be considered in the differential diagnosis of exercise-induced respiratory symptoms.
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